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Leveraging innovation is central for achieving the Sustainable Development Goals agreed by the international community in September 2015 as part of the 2030 Agenda for Sustainable Development. The expansion of the digital revolution into production processes, exemplified by what some have come to call the fourth industrial revolution, promises far-reaching development benefits, but also poses new challenges to inclusiveness. Achieving the Goals will require realizing the potential of these new innovations not only for transforming economies, tackling vulnerability and building resilience (Goal 9), but also for attaining economic growth and decent work (Goal 8) and reducing inequality (Goal 10). To harness these benefits, a strengthened and revitalized global partnership (Goal 17) will be crucial, supported by policies that address a host of emerging issues, from translating innovation into investment to safeguarding universal benefits from productivity growth.